Craig J Thomas Selected Research

Methionine Sulfoxide Reductases

1/2022

Methionine oxidation activates pyruvate kinase M2 to promote pancreatic cancer metastasis.

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Craig J Thomas Research Topics

Disease

61	Neoplasms (Cancer) 04/2024 - 03/2005
7	Rhabdomyosarcoma 11/2023 - 08/2013
5	Lymphoma (Lymphomas) 04/2024 - 01/2010
5	Breast Neoplasms (Breast Cancer) 04/2024 - 01/2006
4	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 04/2024 - 02/2014
4	Lung Neoplasms (Lung Cancer) 04/2024 - 12/2011
4	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2023 - 06/2014
4	Leukemia 01/2023 - 02/2011
4	Carcinogenesis 06/2022 - 10/2012
4	Treatment-Resistant Depressive Disorder 11/2021 - 01/2019
4	Prostatic Neoplasms (Prostate Cancer) 10/2020 - 01/2014
3	Multiple Myeloma 04/2024 - 01/2022
3	Glioma (Gliomas) 07/2023 - 01/2017
3	Ataxia Telangiectasia (Louis Bar Syndrome) 01/2023 - 12/2020
3	Schistosomiasis (Bilharziasis) 10/2009 - 01/2008
2	Chronic Pain 06/2023 - 01/2021
2	Brain Neoplasms (Brain Tumor) 01/2023 - 01/2017
2	Bipolar Disorder (Manic Depressive Psychosis) 01/2022 - 01/2021
2	Major Depressive Disorder (Major Depressive Disorders) 01/2022 - 10/2018
2	Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder) 01/2022 - 01/2021
2	Neoplasm Metastasis (Metastasis) 01/2022 - 11/2019
2	Adenocarcinoma 01/2022 - 01/2022
2	Neuroblastoma 01/2021 - 11/2015
2	Ewing Sarcoma (Sarcoma, Ewing) 01/2020 - 12/2017
2	Tuberculosis (Tuberculoses) 12/2019 - 01/2016
2	Sarcoma (Soft Tissue Sarcoma) 01/2018 - 12/2017
2	Schizophrenia (Dementia Praecox) 01/2016 - 07/2012
2	Marfan Syndrome (Marfan's Syndrome) 10/2015 - 04/2011
2	Thyroid Neoplasms (Thyroid Cancer) 07/2010 - 07/2009
2	Hyperthyroidism 07/2010 - 12/2008
1	Burkitt Lymphoma (Burkitt's Lymphoma) 04/2024
1	Adrenocortical Carcinoma 03/2024
1	Eye Neoplasms (Eye Cancer) 11/2023
1	Uveal melanoma 11/2023
1	Mesothelioma 11/2023
1	Necrosis 11/2023
1	Mitochondrial Diseases (Mitochondrial Disease) 07/2023

Drug/Important Bio-Agent (IBA)

10	Proteins (Proteins, Gene)FDA Link 07/2023 - 07/2009
9	Drug CombinationsIBA 11/2023 - 10/2012
9	Protein Isoforms (Isoforms)IBA 01/2022 - 02/2010
9	EnzymesIBA 12/2021 - 03/2005
8	Phosphotransferases (Kinase)IBA 01/2023 - 05/2008
8	Pyruvate KinaseIBA 01/2022 - 02/2010
6	Ketamine FDA LinkGeneric 06/2023 - 10/2018
6	EsketamineIBA 01/2022 - 10/2018
4	ibrutinibIBA 11/2021 - 02/2014
3	6-hydroxynorketamineIBA 06/2023 - 01/2019
3	Mechanistic Target of Rapamycin Complex 1IBA 10/2022 - 01/2021
3	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 06/2022 - 01/2018
3	Antidepressive Agents (Antidepressants)IBA 01/2022 - 10/2018
3	Type I DNA Topoisomerases (Topoisomerase I)IBA 12/2021 - 03/2005
3	Transcription Factors (Transcription Factor)IBA 01/2020 - 01/2017
3	Histones (Histone)IBA 11/2019 - 12/2010
3	DNA (Deoxyribonucleic Acid)IBA 09/2016 - 03/2005
3	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 10/2015 - 01/2006
2	Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA 04/2024 - 01/2023
2	Tyrosine Kinase InhibitorsIBA 04/2024 - 06/2022
2	NAD (NADH)IBA 11/2023 - 01/2020
2	Analgesics (Analgesic Drugs)IBA 06/2023 - 01/2021
2	8- (6- methoxypyridin- 3- yl)- 3- methyl- 1- (4- piperazin- 1- yl- 3- trifluoromethylphenyl)- 1,3- dihydroimidazo(4,5- c)quinolin- 2- oneIBA 04/2023 - 01/2022
2	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2023 - 11/2018
2	pevonedistatIBA 01/2023 - 01/2023
2	Amino Acids FDA Link 10/2022 - 01/2022
2	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2022 - 11/2018
2	Agammaglobulinaemia Tyrosine KinaseIBA 11/2021 - 12/2017
2	Interleukin-2 (IL2)IBA 01/2021 - 10/2015
2	trametinibIBA 01/2021 - 01/2018
2	CytokinesIBA 01/2021 - 04/2015
2	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2020 - 08/2013
2	Nicotinamide PhosphoribosyltransferaseIBA 01/2020 - 12/2017
2	Aspartic Acid (Aspartate)FDA Link 11/2018 - 11/2016
2	GlutaminaseIBA 11/2018 - 11/2017
2	Glutamine (L-Glutamine)FDA Link 11/2018 - 10/2017
2	Reactive Oxygen Species (Oxygen Radicals)IBA 10/2017 - 12/2011
2	ruxolitinibIBA 02/2016 - 10/2015
2	navitoclaxIBA 02/2016 - 10/2015
2	Neuregulin-1 (Neuregulin 1)IBA 01/2016 - 07/2012
2	Interleukin-15 (Interleukin 15)IBA 10/2015 - 08/2013
2	1- (4- dimethylaminomethylphenyl)- 8,9- dihydro- 7H- 2,7,9a- benzo(cd)azulen- 6- oneIBA 06/2014 - 01/2006
2	IsoenzymesIBA 11/2011 - 02/2010
2	Tyrosine (L-Tyrosine)FDA Link 04/2011 - 12/2010
2	tofacitinibIBA 04/2011 - 02/2011
2	Thyrotropin Receptors (Thyrotropin Receptor)IBA 07/2010 - 12/2008
1	GlucocorticoidsIBA 04/2024
1	src-Family KinasesIBA 04/2024
1	Ubiquitin-Activating Enzymes (Ubiquitin-Activating Enzyme)IBA 03/2024
1	venetoclaxIBA 03/2024
1	TAK-243IBA 03/2024
1	Cytotoxins (Cytolysins)IBA 03/2024
1	Mitotane (Lysodren)FDA Link 03/2024
1	TEA Domain Transcription FactorsIBA 11/2023
1	OT-82IBA 11/2023
1	futibatinibIBA 08/2023
1	RNA (Ribonucleic Acid)IBA 07/2023
1	Investigational DrugsIBA 07/2023
1	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 07/2023
1	Dihydrotachysterol (AT 10)IBA 06/2023

Therapy/Procedure

23	Therapeutics 04/2024 - 01/2008
8	Drug Therapy (Chemotherapy) 01/2023 - 03/2005
1	Precision Medicine 07/2023